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1. By the nature of heart failure
By the nature of cardiac arrest: in the Normacor® group, asystole is more frequent than in the Custodiol group, the difference is statistically significant. 97.5 % in the Normacor® group vs 82.2 % in the Custodiol group (*P<0.05; P=0.0322).
2. By the nature of the rhythm recovery
By the nature of the rhythm recovery: in the Normacor® group, defibrillation is less frequent than in the Custodiol group, the difference is statistically significant. Spontaneous recovery of the heart function in the Normacor® group occurred in 97.5 % versus 53.3 % in the Custodiol group (***P <0.001; P <0.0001).
3. By the use of cardiotonic support (yes/no)
By the use of cardiotonic support (yes/no), a statistically significant difference (* P <0.05; P = 0.0452) was showed. At the intraoperative stage, it had to be used more rarely in the Normacor® group, the difference is statistically reliable. In the Normacor® group, cardiotonic therapy was used in 47.5 % of cases. In the Custodiol group - in 71.1 % of cases. This proves the better protection of the heart with Normacor® by one of the main parameters, frequency of the use of cardiotonic therapy.
4. By the biochemical exponents of arterial blood (pH)
A statistically reliable difference between the Normacor® and Custodiol groups by a number of biochemical exponents of arterial and venous blood was found.
Statistically significant differences in pH in the Normacor® and Custodiol groups were identified at the main stage of the surgery (mean value 7.436 in the Normacor® group vs 7.327 in the Custodiol group, *** P <0.001; P <0.0001), and immediately after the surgery (mean value 7.412 in the Normacor® group vs 7.442 in the Custodiol group, ** P <0.01; P = 0.0056) in the arterial blood.
5. By the biochemical exponents of arterial and venous blood (BE)
Statistically significant differences in BE of the arterial blood in the Normacor® and Custodiol groups were identified at the main stage of the surgery (mean value 1.020 mmol/l in the Normacor® group vs -3.724 mmol/l in the Custodiol group, *** P <0.001; P <0.0001), and of the venous blood (mean value 1.685 mmol/l in the Normacor® group vs -2.160 mmol/l in the Custodiol group, ** P <0.001; P = 0.0001).
6. By the duration of artificial lung ventilation (ALV)
The mean duration of ALV in the Normacor® group was 9.68 hours vs 10.72 hours in the Custodiol group (* P <0.05; P = 0.0376).
